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Pouchology.org

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IPAA / Pouch Literature Collection
A curated collection of peer-reviewed literature on the ileal pouch-anal anastomosis (IPAA) — the restorative surgical alternative to permanent ileostomy for ulcerative colitis and familial polyposis.
Searches title, author, abstract, and snippet — full-text search coming soon.
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What is Pouchology?

Pouchology is an AI-curated collection and searchable knowledge base of 1,297 peer-reviewed publications on the ileal pouch-anal anastomosis (IPAA, or "J-pouch"). It covers the full scope of pouch surgery: operative technique, complications, quality of life, long-term outcomes, pouchitis, fertility, revisional surgery, and emerging topics like biologics and robotic approaches.

This collection spans 40 years (1987–2026) and includes full-text search across PDF extracts. Papers are indexed by first author, year, PMID, and searchable abstract and full text. This is a research tool — enter any clinical question above to find relevant evidence.

Complications
1,082 studies
Quality of Life
833 studies
Crohn's of the Pouch
808 studies
Pouchitis
763 studies
Pouch Survival
711 studies
FAP
693 studies
Anastomotic Leak
679 studies
Pouch Excision
656 studies
Dysplasia & Cancer
535 studies
Obstruction
513 studies
Incontinence
509 studies
Pelvic Sepsis
503 studies
Stricture
481 studies
Fistula
473 studies
Mucosectomy
398 studies
Biologics
388 studies
Sexual Function
286 studies
Continent Ileostomy
280 studies
MIS / Robotic
204 studies
Afferent Limb
165 studies
Cuffitis
151 studies
Robotic Surgery
112 studies
Irritable Pouch
94 studies
Fertility & Pregnancy
75 studies
Microbiome
69 studies
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PouchRAG — AI-Powered Q&A

Ask clinical questions in plain language and get evidence-based answers synthesized from over 900 IPAA publications, with cited sources.

Coming Soon

PouchRAG uses retrieval-augmented generation (RAG) — an AI technique that searches the literature collection first, then generates an answer grounded in the actual studies it finds, rather than relying on general knowledge alone.

In the meantime, use Search Collection to find papers by keyword.

Why Pouchology?

Ileal pouch–anal anastomosis (IPAA) is one of the most complex reconstructive procedures in gastrointestinal surgery. The published literature on pouch surgery spans nearly four decades, thousands of papers, and dozens of subspecialty topics—from pouchitis and fistula management to fertility, robotic technique, and long-term quality of life.

Yet this knowledge is scattered across journals, hard to search, and often inaccessible to the clinicians and patients who need it most.

Pouchology was created to solve this problem. It is an AI-curated collection and searchable knowledge base of over 900 peer-reviewed publications on the ileal pouch, indexed by topic, author, year, and PMID. Every paper in the collection has been extracted from PDF, classified by study type, and made searchable across abstracts and full text.

The topic summaries and evidence overviews you see on this site were generated by artificial intelligence to help users quickly orient to each area of pouch literature. They are not a substitute for reading the primary sources—they are a starting point.

Pouchology is a project of the iPouch Consortium, an international quality improvement initiative dedicated to advancing the care of pouch patients worldwide.

About the Founder

Stefan D. Holubar, MD

Stefan D. Holubar, MD, MS, FACS, FASCRS

Professor of Surgery • Case Western Reserve University and Cleveland Clinic Lerner College of Medicine

Stefan Holubar brings a unique perspective to pouch surgery: he is both a fellowship-trained colorectal surgeon specializing in ileal pouch procedures and himself a pouch patient. This dual lived experience—from both sides of the operating table—drives his commitment to ensuring that every patient who needs a pouch receives the highest quality of care.

Dr. Holubar is co-PI of the Crohn's & Colitis Foundation IBD-SIRCQ, co-PI of the ACS-NSQIP IBD Collaborative (26 sites nationally), founder of the iPouch Consortium, and has authored over 300 peer-reviewed publications, the majority focused on IBD surgical outcomes. His research spans pouch volume–outcome relationships, risk prediction, benchmarking, and the application of AI to surgical quality improvement.

Pouchology represents his vision of making the full scope of pouch literature accessible, searchable, and useful—for surgeons, gastroenterologists, trainees, and patients alike.